Bringing CLARITY to gray matter atrophy
نویسندگان
چکیده
منابع مشابه
Bringing CLARITY to gray matter atrophy
Gray matter atrophy has been shown to be a strong correlate to clinical disability in multiple sclerosis (MS) and its most commonly used animal model, experimental autoimmune encephalomyelitis (EAE). However, the relationship between gray mater atrophy and the spinal cord pathology often observed in EAE has never been established. Here EAE was induced in Thy1.1-YFP mice and their brains imaged ...
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34 Courtney Oare is a 2017 graduate of Purdue University who majored in Radiological Health Sciences with a concentration in Medical Physics. In the School of Health Sciences Honors Program, she partook in research for three years with an interest in imaging and evaluation of disease. Outside of coursework and research, she served as an Ambassador for the College of Health and Human Sciences, w...
متن کاملGray Matter Atrophy Associated With Motor Dysfunction
34 Courtney Oare is a 2017 graduate of Purdue University who majored in Radiological Health Sciences with a concentration in Medical Physics. In the School of Health Sciences Honors Program, she partook in research for three years with an interest in imaging and evaluation of disease. Outside of coursework and research, she served as an Ambassador for the College of Health and Human Sciences, w...
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Gray matter atrophy is an important correlate to clinical disability in multiple sclerosis (MS), and many treatment trials include atrophy as an outcome measure. Atrophy has been shown to occur in experimental autoimmune encephalomyelitis (EAE), the most commonly used animal model of MS. The clinical severity of EAE is reduced in estrogen-reated mice, but it remains unknown whether estrogen tre...
متن کاملGray matter atrophy in multiple sclerosis: a longitudinal study.
OBJECTIVE To determine gray matter (GM) atrophy rates in multiple sclerosis (MS) patients at all stages of disease, and to identify predictors and clinical correlates of GM atrophy. METHODS MS patients and healthy control subjects were observed over 4 years with standardized magnetic resonance imaging (MRI) and neurological examinations. Whole-brain, GM, and white matter atrophy rates were ca...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2014
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2014.07.017